URETERO-PELVIC JUNCTION OBSTRUCTION IN CHILDREN: IS VASCULAR HITCH AN EFFECTIVE AND SAFE SOLUTIONS IN VERY LONG TERM OUTCOME? REPORT OF 25 YEARS FOLLOW-UP

Vascular (VH) according to Hellstrom-Chapman technique is considered a safe and effective alternative approach to pure extrinsic Ureteropelvic Junction Obstruction (UPJO) with good results in short and medium term, but few data are available on long and verylong term outcomes.Our aim is to evaluate VH long and very-long term outcomes in patients tr

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with short life expectancy and no effective therapy.We previously identified upregulated miR-124 in NSC-34-motor neurons (MNs) expressing human SOD1-G93A (mSOD1) and established its implication in mSOD1 MN degeneration and glial cell activation.When anti-miR-124-treated mSOD1 MN (pr

Zika virus Medical Thermometers (ZIKV), a mosquito-transmitted Flavivirus, emerged in the last decade causing serious diseases and affecting human health globally.Currently, no licensed vaccines or antivirals are available to combat ZIKV, although several vaccine candidates are in the pipeline.In recent years, the presence of non-canonical G-quadru

Since its inception, the 2019 coronavirus disease (Covid-19) outbreak has become a major health problem.At the same time, countries worldwide have been waiting for a Covid-19 vaccine to be sufficiently available.When the Covid-19 vaccine became available, several countries began to adopt mandatory Covid-19 vaccination policies.However, mandatory Co

The origin and the neural pathways involved in chronic neuropathic pain are still not extensively understood.For this reason, despite the wide variety of pain medications available on the market, neuropathic pain is challenging to treat.The present therapeutic alternative considered as the gold standard Moulds and Bakeware for many kinds of chronic